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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
15.45
Human Site:
S595
Identified Species:
26.15
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S595
K
E
G
R
P
I
K
S
V
S
E
R
L
S
S
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S595
K
E
G
R
P
I
K
S
V
S
E
R
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S594
K
E
G
R
P
I
K
S
V
S
E
R
L
S
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
S603
K
E
G
G
P
V
K
S
L
S
E
R
I
S
S
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
R14
A
E
H
E
R
F
K
R
I
D
F
A
H
S
K
Chicken
Gallus gallus
Q9I920
1142
126164
L365
V
K
S
S
S
E
P
L
V
H
N
P
A
H
E
Frog
Xenopus laevis
Q9DEY9
1364
152305
A555
Q
Y
P
T
I
R
E
A
Q
L
D
S
R
N
K
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
G484
D
S
D
C
I
I
N
G
V
E
T
P
G
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
A666
E
Q
M
H
S
Q
A
A
A
N
K
S
R
V
S
Honey Bee
Apis mellifera
XP_396209
961
109321
R184
E
D
R
C
K
H
L
R
N
F
Q
I
E
I
L
Nematode Worm
Caenorhab. elegans
O18017
988
110641
G211
D
M
H
G
R
F
R
G
F
L
Q
D
D
S
E
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
S595
S
S
T
V
T
P
R
S
V
S
S
K
R
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
G607
I
T
E
R
K
L
T
G
D
N
E
H
P
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
0
N.A.
20
6.6
0
13.3
N.A.
6.6
0
6.6
26.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
26.6
13.3
33.3
20
N.A.
40
20
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
15
8
0
0
8
8
0
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
8
0
0
0
0
0
8
8
8
8
8
0
0
% D
% Glu:
15
36
8
8
0
8
8
0
0
8
36
0
8
0
15
% E
% Phe:
0
0
0
0
0
15
0
0
8
8
8
0
0
0
0
% F
% Gly:
0
0
29
15
0
0
0
22
0
0
0
0
8
8
0
% G
% His:
0
0
15
8
0
8
0
0
0
8
0
8
8
8
0
% H
% Ile:
8
0
0
0
15
29
0
0
8
0
0
8
8
8
0
% I
% Lys:
29
8
0
0
15
0
36
0
0
0
8
8
0
0
15
% K
% Leu:
0
0
0
0
0
8
8
8
8
15
0
0
22
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
15
8
0
0
8
0
% N
% Pro:
0
0
8
0
29
8
8
0
0
0
0
15
8
8
8
% P
% Gln:
8
8
0
0
0
8
0
0
8
0
15
0
0
0
0
% Q
% Arg:
0
0
8
29
15
8
15
15
0
0
0
29
22
0
0
% R
% Ser:
8
15
8
8
15
0
0
36
0
36
8
15
0
43
43
% S
% Thr:
0
8
8
8
8
0
8
0
0
0
8
0
0
8
8
% T
% Val:
8
0
0
8
0
8
0
0
43
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _